Rapid mRNA-Display Selection of an IL-6 Inhibitor Using Continuous-Flow Magnetic Separation

Since the invention of hybridoma technology, methods for generating affinity reagents that bind specific target molecules have revolutionized biology and medicine.([1]) In the postgenomic era, there is a pressing need to accelerate the pace of ligand discovery to elucidate the functions of a rapidly...

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Autori principali: Olson, C. Anders, Adams, Jonathan D., Takahashi, Terry T., Qi, Hangfei, Howell, Shannon M., Wu, Ting-Ting, Roberts, Richard W., Sun, Ren, Soh, H. Tom
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747967/
https://ncbi.nlm.nih.gov/pubmed/21761516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201101149
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