Receiver Operating Characteristic Analysis of HLA, CTLA4, and Insulin Genotypes for Type 1 Diabetes

OBJECTIVE: This study assessed the ability to distinguish between type 1 diabetes–affected individuals and their unaffected relatives using HLA and single nucleotide polymorphism (SNP) genotypes. RESEARCH DESIGN AND METHODS: Eight models, ranging from only the high-risk DR3/DR4 genotype to all signi...

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Bibliographic Details
Main Authors: Valdes, Ana M., Varney, Michael D., Erlich, Henry A., Noble, Janelle A.
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747897/
https://ncbi.nlm.nih.gov/pubmed/23628620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-2284
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