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Genetics of the HLA Region in the Prediction of Type 1 Diabetes

Type 1 diabetes (T1D) is one of the most widely studied complex genetic disorders, and the genes in HLA are reported to account for approximately 40% to 50% of the familial aggregation of T1D. The major genetic determinants of this disease are polymorphisms of class II HLA genes encoding DQ and DR....

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書誌詳細
主要な著者: Noble, Janelle A., Valdes, Ana M.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233362/
https://ncbi.nlm.nih.gov/pubmed/21912932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-011-0223-x
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