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Genetics of the HLA Region in the Prediction of Type 1 Diabetes
Type 1 diabetes (T1D) is one of the most widely studied complex genetic disorders, and the genes in HLA are reported to account for approximately 40% to 50% of the familial aggregation of T1D. The major genetic determinants of this disease are polymorphisms of class II HLA genes encoding DQ and DR....
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233362/ https://ncbi.nlm.nih.gov/pubmed/21912932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11892-011-0223-x |
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