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Modulation by Dietary Fat and Carbohydrate of IRS1 Association With Type 2 Diabetes Traits in Two Populations of Different Ancestries

OBJECTIVE: Insulin receptor substrate 1 (IRS1) is central to insulin signaling pathways. This study aimed to examine the association of IRS1 variants with insulin resistance (IR) and related phenotypes, as well as potential modification by diet. RESEARCH DESIGN AND METHODS: Two IRS1 variants (rs7578...

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Bibliographische Detailangaben
Hauptverfasser: Zheng, Ju-Sheng, Arnett, Donna K., Parnell, Laurence D., Smith, Caren E., Li, Duo, Borecki, Ingrid B., Tucker, Katherine L., Ordovás, José M., Lai, Chao-Qiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747864/
https://ncbi.nlm.nih.gov/pubmed/23596181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-2607
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