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Modulation by Dietary Fat and Carbohydrate of IRS1 Association With Type 2 Diabetes Traits in Two Populations of Different Ancestries

OBJECTIVE: Insulin receptor substrate 1 (IRS1) is central to insulin signaling pathways. This study aimed to examine the association of IRS1 variants with insulin resistance (IR) and related phenotypes, as well as potential modification by diet. RESEARCH DESIGN AND METHODS: Two IRS1 variants (rs7578...

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Main Authors: Zheng, Ju-Sheng, Arnett, Donna K., Parnell, Laurence D., Smith, Caren E., Li, Duo, Borecki, Ingrid B., Tucker, Katherine L., Ordovás, José M., Lai, Chao-Qiang
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747864/
https://ncbi.nlm.nih.gov/pubmed/23596181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-2607
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