Formulating food protein-stabilized indomethacin nanosuspensions into pellets by fluid-bed coating technology: physical characterization, redispersibility, and dissolution

BACKGROUND: Drug nanosuspensions are very promising for enhancing the dissolution and bioavailability of drugs that are poorly soluble in water. However, the poor stability of nanosuspensions, reflected in particle growth, aggregation/agglomeration, and change in crystallinity state greatly limits t...

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Detalles Bibliográficos
Main Authors: He, Wei, Lu, Yi, Qi, Jianping, Chen, Lingyun, Yin, Lifang, Wu, Wei
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747851/
https://ncbi.nlm.nih.gov/pubmed/23983465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S46207
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