Novel redispersible nanosuspensions stabilized by co-processed nanocrystalline cellulose–sodium carboxymethyl starch for enhancing dissolution and oral bioavailability of baicalin

BACKGROUND: To improve the dissolution and bioavailability of poorly soluble drugs, novel nanosuspensions using co-processed nanocrystalline cellulose–sodium carboxymethyl starch (NCCS) as a synergetic stabilizer were first designed. METHODS: Co-processed NCCS was prepared by means of homogenization...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Xie, Jin, Luo, Yijing, Liu, Yang, Ma, Yueqin, Yue, Pengfei, Yang, Ming
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2019
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6322498/
https://ncbi.nlm.nih.gov/pubmed/30655668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S184374
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