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Ultrasound with microbubbles enhances gene expression of plasmid DNA in the liver via intraportal delivery

Current ultrasound (US)-mediated gene delivery methods are inefficient due, in part, to a lack of US optimization. We systematically explored the use of microbubbles (MBs), US parameters and plasmid delivery routes to improve gene transfer into the mouse liver. Co-presentation of plasmid DNA (pDNA),...

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Main Authors: Shen, ZP, Brayman, AA, Chen, L, Miao, CH
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747825/
https://ncbi.nlm.nih.gov/pubmed/18385766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2008.51
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