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Factor VII activating protease (FSAP) promotes the proteolysis and inhibition of tissue factor pathway inhibitor (TFPI)

OBJECTIVES: Factor VII activating protease (FSAP) activates FVII as well as pro-urokinase and inhibits platelet-derived growth factor-BB, thus regulating haemostasis- and remodeling-associated processes in the vasculature. A genetic variant of FSAP (Marburg I polymorphism) results in low enzymatic a...

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Detalles Bibliográficos
Main Authors: Kanse, Sandip M., Declerck, Paul J., Ruf, Wolfram, Broze, George, Etscheid, Michael
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747817/
https://ncbi.nlm.nih.gov/pubmed/22116096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.238394
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