HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy

Several clinical trials have shown that oncolytic herpes simplex virus type 1 (oHSV-1) can be safely administered to patients. However, virus replication in tumor tissue has generally not been monitored in these oHSV clinical trials, and the data suggest that its oncolytic potency needs to be improv...

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Autori principali: Li, H, Nakashima, H, Decklever, T D, Nace, R A, Russell, S J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747331/
https://ncbi.nlm.nih.gov/pubmed/23868101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.43
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