hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca(2+) entry and calpain 2

Golgi antiapoptotic proteins (GAAPs) are highly conserved Golgi membrane proteins that inhibit apoptosis and promote Ca(2+) release from intracellular stores. Given the role of Ca(2+) in controlling cell adhesion and motility, we hypothesized that human GAAP (hGAAP) might influence these events. In...

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Detalhes bibliográficos
Main Authors: Saraiva, Nuno, Prole, David L., Carrara, Guia, Johnson, Benjamin F., Taylor, Colin W., Parsons, Maddy, Smith, Geoffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747308/
https://ncbi.nlm.nih.gov/pubmed/23940116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201301016
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