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Sexually Dimorphic Genome-Wide Binding of Retinoid X Receptor alpha (RXRα) Determines Male-Female Differences in the Expression of Hepatic Lipid Processing Genes in Mice

Many hepatic functions including lipid metabolism, drug metabolism, and inflammatory responses are regulated in a sex-specific manner due to distinct patterns of hepatic gene expression between males and females. Regulation for the majority of these genes is under control of Nuclear Receptors (NRs)....

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Autors principals: Kosters, Astrid, Sun, Deqiang, Wu, Hao, Tian, Feng, Felix, Julio C., Li, Wei, Karpen, Saul J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747242/
https://ncbi.nlm.nih.gov/pubmed/23977068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071538
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