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Ca(2+)/Calmodulin-Dependent Protein Kinase II Contributes to Hypoxic Ischemic Cell Death in Neonatal Hippocampal Slice Cultures

We have recently shown that p38MAP kinase (p38MAPK) stimulates ROS generation via the activation of NADPH oxidase during neonatal hypoxia-ischemia (HI) brain injury. However, how p38MAPK is activated during HI remains unresolved and was the focus of this study. Ca(2+)/calmodulin-dependent protein ki...

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Detalhes bibliográficos
Main Authors: Lu, Qing, Harris, Valerie A., Sun, Xutong, Hou, Yali, Black, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747161/
https://ncbi.nlm.nih.gov/pubmed/23976956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070750
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