Disruption of microRNA Biogenesis Confers Resistance to ER Stress-Induced Cell Death Upstream of the Mitochondrion

Global downregulation of microRNAs (miRNAs) is a common feature of human tumors and has been shown to enhance cancer progression. Several components of the miRNA biogenesis machinery (XPO5, DICER and TRBP) have been shown to act as haploinsufficient tumor suppressors. How the deregulation of miRNA b...

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Bibliografiske detaljer
Main Authors: Cawley, Karen, Logue, Susan E., Gorman, Adrienne M., Zeng, Qingping, Patterson, John, Gupta, Sanjeev, Samali, Afshin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747093/
https://ncbi.nlm.nih.gov/pubmed/23977393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073870
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