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A Reinforcing Circuit Action of Extrasynaptic GABA(A) Receptor Modulators on Cerebellar Granule Cell Inhibition

GABA(A) receptors (GABARs) are the targets of a wide variety of modulatory drugs which enhance chloride flux through GABAR ion channels. Certain GABAR modulators appear to acutely enhance the function of δ subunit-containing GABAR subtypes responsible for tonic forms of inhibition. Here we identify...

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Detalhes bibliográficos
Main Authors: Santhakumar, Vijayalakshmi, Meera, Pratap, Karakossian, Movses H., Otis, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747091/
https://ncbi.nlm.nih.gov/pubmed/23977374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072976
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