S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB(1)

S100A8 and S100A9 are cytoplasmic proteins expressed by phagocytes. High concentrations of these proteins have been correlated with various inflammatory conditions, including autoimmune diseases such as rheumatoid arthritis and Crohn’s disease, as well as autoinflammatory diseases. In the present st...

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Bibliografiske detaljer
Main Authors: Simard, Jean-Christophe, Cesaro, Annabelle, Chapeton-Montes, Julie, Tardif, Mélanie, Antoine, Francis, Girard, Denis, Tessier, Philippe A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747084/
https://ncbi.nlm.nih.gov/pubmed/23977231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072138
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