Human Glioblastoma Multiforme: p53 Reactivation by a Novel MDM2 Inhibitor

Cancer development and chemo-resistance are often due to impaired functioning of the p53 tumor suppressor through genetic mutation or sequestration by other proteins. In glioblastoma multiforme (GBM), p53 availability is frequently reduced because it binds to the Murine Double Minute-2 (MDM2) oncopr...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Costa, Barbara, Bendinelli, Sara, Gabelloni, Pamela, Da Pozzo, Eleonora, Daniele, Simona, Scatena, Fabrizio, Vanacore, Renato, Campiglia, Pietro, Bertamino, Alessia, Gomez-Monterrey, Isabel, Sorriento, Daniela, Del Giudice, Carmine, Iaccarino, Guido, Novellino, Ettore, Martini, Claudia
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747081/
https://ncbi.nlm.nih.gov/pubmed/23977270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072281
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares