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Differential Modulation of Functional Dynamics and Allosteric Interactions in the Hsp90-Cochaperone Complexes with p23 and Aha1: A Computational Study

Allosteric interactions of the molecular chaperone Hsp90 with a large cohort of cochaperones and client proteins allow for molecular communication and event coupling in signal transduction networks. The integration of cochaperones into the Hsp90 system is driven by the regulatory mechanisms that mod...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Blacklock, Kristin, Verkhivker, Gennady M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3747073/
https://ncbi.nlm.nih.gov/pubmed/23977182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071936
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