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Human β-Defensin 3 Peptide is Increased and Redistributed in Crohn's Ileitis

BACKGROUND: Antimicrobial peptides (AMPs) maintain a sterile environment in intestinal crypts, limiting microbial colonization and invasion. Decreased AMP expression is proposed to increase the risk for inflammatory bowel disease. Expression and function of inducible AMPs, human β-defensin 2 and 3 (...

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Detalhes bibliográficos
Main Authors: Meisch, Jeffrey P., Nishimura, Michiko, Vogel, Ryan M., Sung, Hannah C., Bednarchik, Beth A., Ghosh, Santosh K., Fu, Pingfu, McCormick, Thomas, Weinberg, Aaron, Levine, Alan D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746836/
https://ncbi.nlm.nih.gov/pubmed/23511030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0b013e318280b11a
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