Increased Serum Type I Interferon Activity in Organ-Specific Autoimmune Disorders: Clinical, Imaging, and Serological Associations

Background: Activation of the type I interferon (IFN) pathway has been implicated in the pathogenesis of systemic autoimmune disorders but its role in the pathogenesis of organ-specific autoimmunity is limited. We tested the hypothesis that endogenous expression of type I IFN functional activity con...

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Hauptverfasser: Mavragani, Clio P., Niewold, Timothy B., Chatzigeorgiou, Antonis, Danielides, Stamatina, Thomas, Dimitrios, Kirou, Kyriakos A., Kamper, Elli, Kaltsas, Grigorios, Crow, Mary K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746787/
https://ncbi.nlm.nih.gov/pubmed/23966997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00238
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