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Condensation reactions of guanidines with bis-electrophiles: Formation of highly nitrogenous heterocycles()

2-Amino-1,4-dihydropyrimidines were reacted with bis-electrophiles to produce novel fused bi-pyrimidine, pyrimido-aminotriazine, and pyrimido-sulfonamide scaffolds. In addition, a quinazoline library was constructed using a guanidine Atwal-Biginelli reaction with 1-(quinazolin-2-yl)guanidines. The p...

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Detalhes bibliográficos
Main Authors: Arnold, David M., LaPorte, Matthew G., Anderson, Shelby M., Wipf, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746774/
https://ncbi.nlm.nih.gov/pubmed/23976798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2013.04.127
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