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Process optimization and evaluation of novel baicalin solid nanocrystals
The objective of this study was to prepare baicalin solid nanocrystals (BCN-SNS) to enhance oral bioavailability of baicalin. A Box–Behnken design approach was used for process optimization. The physicochemical properties and pharmacokinetics of the optimal BCN-SNS were investigated. Multiple linear...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3746734/ https://ncbi.nlm.nih.gov/pubmed/23976849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S44924 |
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