Expression of anti-HVEM single-chain antibody on tumor cells induces tumor-specific immunity with long-term memory

Genetic engineering of tumor cells to express immune-stimulatory molecules, including cytokines and co-stimulatory ligands, is a promising approach to generate highly efficient cancer vaccines. The co-signaling molecule, LIGHT, is particularly well suited for use in vaccine development as it deliver...

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Detalhes bibliográficos
Main Authors: Park, Jang-June, Anand, Sudarshan, Zhao, Yuming, Matsumura, Yumiko, Sakoda, Yukimi, Kuramasu, Atsuo, Strome, Scott E., Chen, Lieping, Tamada, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746333/
https://ncbi.nlm.nih.gov/pubmed/21877247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1101-8
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