B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance

T-cell tolerance is the central program that prevents harmful immune responses against self-antigens, in which inhibitory PD-1 signal given by B7-H1 interaction plays an important role. Recent studies demonstrated that B7-H1 binds CD80 besides PD-1, and B7-H1/CD80 interaction also delivers inhibitor...

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Hauptverfasser: Park, Jang-June, Omiya, Ryusuke, Matsumura, Yumiko, Sakoda, Yukimi, Kuramasu, Atsuo, Augustine, Mathew M., Yao, Sheng, Tsushima, Fumihiko, Narazaki, Hidehiko, Anand, Sudarshan, Liu, Yingjia, Strome, Scott E., Chen, Lieping, Tamada, Koji
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2010
Schlagworte:
Immunobiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938239/
https://ncbi.nlm.nih.gov/pubmed/20472828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-265975
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