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B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance
T-cell tolerance is the central program that prevents harmful immune responses against self-antigens, in which inhibitory PD-1 signal given by B7-H1 interaction plays an important role. Recent studies demonstrated that B7-H1 binds CD80 besides PD-1, and B7-H1/CD80 interaction also delivers inhibitor...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society of Hematology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938239/ https://ncbi.nlm.nih.gov/pubmed/20472828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-265975 |
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