Effects of structural analogues of apelin-12 in acute myocardial infarction in rats

OBJECTIVE: To examine cardioprotective effects of Ρ-terminal fragment of adipokine apelin-12 (A12), its novel structural analogue [MeArg(1), NLe(10)]-A12 (I), and [d-Ala(12)]-A12 (II), a putative antagonist of APJ receptor, employing in vivo model of ischemia/reperfusion (I/R) injury. MATERIALS AND...

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Bibliografske podrobnosti
Main Authors: Pisarenko, Oleg I., Serebryakova, Larisa I., Studneva, Irina M., Pelogeykina, Yulia A., Tskitishvili, Olga V., Bespalova, Zhanna D., Sidorova, Maria V., Az’muko, Andrei A., Khatri, Denis N., Pal’keeva, Maria E., Molokoedov, Alexander S.
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications & Media Pvt Ltd 2013
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746303/
https://ncbi.nlm.nih.gov/pubmed/23960425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-500X.114600
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