Effects of structural analogues of apelin-12 in acute myocardial infarction in rats

OBJECTIVE: To examine cardioprotective effects of Ρ-terminal fragment of adipokine apelin-12 (A12), its novel structural analogue [MeArg(1), NLe(10)]-A12 (I), and [d-Ala(12)]-A12 (II), a putative antagonist of APJ receptor, employing in vivo model of ischemia/reperfusion (I/R) injury. MATERIALS AND...

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Main Authors: Pisarenko, Oleg I., Serebryakova, Larisa I., Studneva, Irina M., Pelogeykina, Yulia A., Tskitishvili, Olga V., Bespalova, Zhanna D., Sidorova, Maria V., Az’muko, Andrei A., Khatri, Denis N., Pal’keeva, Maria E., Molokoedov, Alexander S.
Formato: Artigo
Idioma:Inglês
Publicado: Medknow Publications & Media Pvt Ltd 2013
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746303/
https://ncbi.nlm.nih.gov/pubmed/23960425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0976-500X.114600
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