Parental origin of sequence variants associated with complex diseases

Effects of susceptibility variants may depend on from which parent they are inherited. While many associations between sequence variants and human traits have been discovered through genome-wide associations, the impact of parental origin has largely been ignored. Combining genealogy with long range...

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Hlavní autoři: Kong, Augustine, Steinthorsdottir, Valgerdur, Masson, Gisli, Thorleifsson, Gudmar, Sulem, Patrick, Besenbacher, Soren, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Kristinsson, Kari Th., Jonasdottir, Adalbjorg, Frigge, Michael L., Gylfason, Arnaldur, Olason, Pall I., Gudjonsson, Sigurjon A., Sverrisson, Sverrir, Stacey, Simon N., Sigurgeirsson, Bardur, Benediktsdottir, Kristrun R., Sigurdsson, Helgi, Jonsson, Thorvaldur, Benediktsson, Rafn, Olafsson, Jon H., Johannsson, Oskar Th., Hreidarsson, Astradur B., Sigurdsson, Gunnar, Ferguson-Smith, Anne C., Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Stefansson, Kari
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746295/
https://ncbi.nlm.nih.gov/pubmed/20016592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08625
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