MAP1B-dependent Rac activation is required for AMPA receptor endocytosis during long-term depression

The microtubule-associated protein 1B (MAP1B) plays critical roles in neurite growth and synapse maturation during brain development. This protein is well expressed in the adult brain. However, its function in mature neurons remains unknown. We have used a genetically modified mouse model and shRNA...

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Main Authors: Benoist, Marion, Palenzuela, Rocío, Rozas, Carlos, Rojas, Patricio, Tortosa, Elena, Morales, Bernardo, González-Billault, Christian, Ávila, Jesús, Esteban, José A
Formato: Artigo
Idioma:Inglês
Publicado: European Molecular Biology Organization 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746201/
https://ncbi.nlm.nih.gov/pubmed/23881099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.166
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