DPY30 regulates pathways in cellular senescence through ID protein expression

Cellular senescence is an intrinsic defense mechanism to various cellular stresses: while still metabolically active, senescent cells stop dividing and enter a proliferation arrest. Here, we identify DPY30, a member of all mammalian histone H3K4 histone methyltransferases (HMTases), as a key regulat...

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Main Authors: Simboeck, Elisabeth, Gutierrez, Arantxa, Cozzuto, Luca, Beringer, Malte, Caizzi, Livia, M Keyes, William, Di Croce, Luciano
Format: Artigo
Jezik:Inglês
Izdano: European Molecular Biology Organization 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746196/
https://ncbi.nlm.nih.gov/pubmed/23872946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.159
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