HDAC1, a novel marker for benign teratomas

Histone deacetylases (HDACs) are attractive chemotherapy targets, owing to their pro-proliferative activities. However, the finding that loss of HDAC1 promotes teratoma malignancy calls for caution in the use of HDAC inhibitors as cancer therapeutics.

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Bibliographic Details
Main Authors: Simboeck, Elisabeth, Di Croce, Luciano
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020642/
https://ncbi.nlm.nih.gov/pubmed/21124297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.281
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