SIRTUIN 1 AND SIRTUIN 3: PHYSIOLOGICAL MODULATORS OF METABOLISM

The sirtuins are a family of highly conserved NAD(+)-dependent deacetylases that act as cellular sensors to detect energy availability and modulate metabolic processes. Two sirtuins that are central to the control of metabolic processes are mammalian sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3), which ar...

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Main Authors: Nogueiras, Ruben, Habegger, Kirk M., Chaudhary, Nilika, Finan, Brian, Banks, Alexander S., Dietrich, Marcelo O., Horvath, Tamas L., Sinclair, David A., Pfluger, Paul T., Tschöop, Matthias H.
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3746174/
https://ncbi.nlm.nih.gov/pubmed/22811431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physrev.00022.2011
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