Rotenone Upregulates Alpha-Synuclein and Myocyte Enhancer Factor 2D Independently from Lysosomal Degradation Inhibition

Dysfunctions of chaperone-mediated autophagy (CMA), the main catabolic pathway for alpha-synuclein, have been linked to the pathogenesis of Parkinson's disease (PD). Since till now there is limited information on how PD-related toxins may affect CMA, in this study we explored the effect of mito...

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Bibliografiske detaljer
Main Authors: Sala, Gessica, Arosio, Alessandro, Stefanoni, Giovanni, Melchionda, Laura, Riva, Chiara, Marinig, Daniele, Brighina, Laura, Ferrarese, Carlo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745903/
https://ncbi.nlm.nih.gov/pubmed/23984410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/846725
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