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Aberrant O-glycosylation and anti-glycan antibodies in an autoimmune disease IgA nephropathy and breast adenocarcionoma
Glycosylation abnormalities have been observed in autoimmune diseases and cancer. Here, we compare mechanisms of aberrant O-glycosylation, i.e., formation of Tn and sialyl-Tn structures, on MUC1 in breast cancer and on IgA1 in an autoimmune disease, IgA nephropathy. The pathways of aberrant glycosyl...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745718/ https://ncbi.nlm.nih.gov/pubmed/22864623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1082-6 |
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