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Aberrant O-glycosylation and anti-glycan antibodies in an autoimmune disease IgA nephropathy and breast adenocarcionoma

Glycosylation abnormalities have been observed in autoimmune diseases and cancer. Here, we compare mechanisms of aberrant O-glycosylation, i.e., formation of Tn and sialyl-Tn structures, on MUC1 in breast cancer and on IgA1 in an autoimmune disease, IgA nephropathy. The pathways of aberrant glycosyl...

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Hlavní autoři: Horynová, Milada Stuchlová, Raška, Milan, Clausen, Henrik, Novak, Jan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745718/
https://ncbi.nlm.nih.gov/pubmed/22864623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-012-1082-6
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