TGF-β modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment

TGF-β has limited effects on ovarian cancer cells but its contributions to ovarian tumor growth might be mediated through elements of the tumor microenvironment. In the present study, we tested the hypothesis that TGF- modulates ovarian cancer progression by modulating the contribution of cancer-ass...

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Hauptverfasser: Yeung, Tsz-Lun, Leung, Cecilia S., Wong, Kwong-Kwok, Samimi, Goli, Thompson, Melissa S., Liu, Jinsong, Zaid, Tarrik M., Ghosh, Sue, Birrer, Michael J., Mok, Samuel C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745588/
https://ncbi.nlm.nih.gov/pubmed/23824740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0023
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