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TGF-β modulates ovarian cancer invasion by upregulating CAF-derived versican in the tumor microenvironment

TGF-β has limited effects on ovarian cancer cells but its contributions to ovarian tumor growth might be mediated through elements of the tumor microenvironment. In the present study, we tested the hypothesis that TGF- modulates ovarian cancer progression by modulating the contribution of cancer-ass...

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Detalhes bibliográficos
Main Authors: Yeung, Tsz-Lun, Leung, Cecilia S., Wong, Kwong-Kwok, Samimi, Goli, Thompson, Melissa S., Liu, Jinsong, Zaid, Tarrik M., Ghosh, Sue, Birrer, Michael J., Mok, Samuel C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745588/
https://ncbi.nlm.nih.gov/pubmed/23824740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0023
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