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The deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically-induced liver carcinogenesis

Gpbar1 (TGR5), a membrane-bound bile acid receptor, is well known for its roles in regulation of energy homeostasis and glucose metabolism. We recently reported that TGR5 activation inhibits nuclear factor κB (NF-κB)-mediated inflammation. Here we show that TGR5 deficiency enhances chemically-induce...

詳細記述

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書誌詳細
主要な著者: Chen, Wei-Dong, Yu, Donna, Forman, Barry M., Huang, Wendong, Wang, Yan-Dong
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745510/
https://ncbi.nlm.nih.gov/pubmed/22911633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26019
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