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Electrostatic origin of in vitro aggregation of human γ-crystallin

The proteins α-, β-, and γ-crystallins are the major components of the lens in the human eye. Using dynamic light scattering method, we have performed in vitro investigations of protein-protein interactions in dilute solutions of human γ-crystallin and α-crystallin. We find that γ-crystallin spontan...

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Détails bibliographiques
Auteurs principaux: Mohr, Benjamin G., Dobson, Cassidy M., Garman, Scott C., Muthukumar, Murugappan
Format: Artigo
Langue:Inglês
Publié: AIP Publishing LLC 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745490/
https://ncbi.nlm.nih.gov/pubmed/24089726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4816367
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