In Vitro Neutralization of Low Dose Inocula at Physiological Concentrations of a Monoclonal Antibody Which Protects Macaques against SHIV Challenge

BACKGROUND: Passive transfer of antibodies can be protective in the simian human immunodeficiency virus (SHIV) – rhesus macaque challenge model. The human monoclonal antibody IgG1 b12 neutralizes human immunodeficiency type 1 (HIV-1) in vitro and protects against challenge by SHIV. Our hypothesis is...

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Bibliographische Detailangaben
Hauptverfasser: Davis, David, Koornstra, Wim, Fagrouch, Zahra, Verschoor, Ernst J., Heeney, Jonathan L., Bogers, Willy M. J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745472/
https://ncbi.nlm.nih.gov/pubmed/23977339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072702
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