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Allosteric Coupling in the Bacterial Adhesive Protein FimH
The protein FimH is expressed by the majority of commensal and uropathogenic strains of Escherichia coli on the tips of type 1 fimbriae and mediates adhesion via a catch bond to its ligand mannose. Crystal structures of FimH show an allosteric conformational change, but it remains unclear whether al...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745355/ https://ncbi.nlm.nih.gov/pubmed/23821547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.461376 |
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