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Membrane Damage by an α-Helical Pore-forming Protein, Equinatoxin II, Proceeds through a Succession of Ordered Steps

Actinoporin equinatoxin II (EqtII) is an archetypal example of α-helical pore-forming toxins that porate cellular membranes by the use of α-helices. Previous studies proposed several steps in the pore formation: binding of monomeric protein onto the membrane, followed by oligomerization and insertio...

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Detalhes bibliográficos
Main Authors: Rojko, Nejc, Kristan, Katarina Č., Viero, Gabriella, Žerovnik, Eva, Maček, Peter, Dalla Serra, Mauro, Anderluh, Gregor
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745318/
https://ncbi.nlm.nih.gov/pubmed/23803608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.481572
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