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The Role of Mammalian Sirtuins in the Regulation of Metabolism, Aging, and Longevity
Ever since the discovery of sirtuins a decade ago, interest in this family of NAD-dependent deacetylases has exploded, generating multiple lines of evidence implicating sirtuins as evolutionarily conserved regulators of lifespan. In mammals, it has been established that sirtuins regulate physiologic...
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Hauptverfasser: | , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2011
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745303/ https://ncbi.nlm.nih.gov/pubmed/21879449 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-21631-2_7 |
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