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Enhancement of the dissolution of albendazole from pellets using MTR technique

Albendazole (ABZ), a broad-spectrum anthelmintic agent, is poorly absorbed after oral administration due to its low aqueous solubility. The aim of this study was to improve albendazole dissolution rate by formulating avicel pellets loaded with 10% w/w drug using extrusion/spheronization technique. I...

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Hlavní autoři: Ibrahim, Mohamed A., Al-Anazi, Fars K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745170/
https://ncbi.nlm.nih.gov/pubmed/23960837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2012.03.001
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