Self-nanoemulsifying ramipril tablets: a novel delivery system for the enhancement of drug dissolution and stability

Background: Ramipril (RMP) suffers from poor aqueous solubility along with sensitivity to mechanical stress, heat, and moisture. The aim of the current study is to improve RMP solubility and stability by designing solid self-nanoemulsifying drug delivery system (S-SNEDDS) as tablet. Methods: The dru...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Nanomedicine
Prif Awduron: Alhasani, Khalid F, Kazi, Mohsin, Ibrahim, Mohamed Abbas, Shahba, Ahmad A, Alanazi, Fars K
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove 2019
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645612/
https://ncbi.nlm.nih.gov/pubmed/31409997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S203311
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