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Designing an extended release waxy matrix tablet containing nicardipine–hydroxy propyl β cyclodextrin complex
AIM: The current study aimed to prepare a sustained release tablet for a drug which has poor solubility in alkaline medium using complexation with cyclodextrin. Nicardipine hydrochloride (NC) a weak basic drug was chosen as a model drug for this study. METHOD: Firstly the most suitable binary system...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3745040/ https://ncbi.nlm.nih.gov/pubmed/23960765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2011.05.004 |
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