Designing an extended release waxy matrix tablet containing nicardipine–hydroxy propyl β cyclodextrin complex

AIM: The current study aimed to prepare a sustained release tablet for a drug which has poor solubility in alkaline medium using complexation with cyclodextrin. Nicardipine hydrochloride (NC) a weak basic drug was chosen as a model drug for this study. METHOD: Firstly the most suitable binary system...

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Библиографические подробности
Главные авторы: Al-Zein, Hind, Sakeer, Khalil, Alanazi, Fars K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3745040/
https://ncbi.nlm.nih.gov/pubmed/23960765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2011.05.004
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