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Simple and rapid HPLC method for simultaneous determination of atenolol and chlorthalidone in spiked human plasma

A simple, sensitive and rapid chromatographic method was developed and validated for the simultaneous quantification of atenolol and chlorthalidone in human plasma using hydrochlorothiazide as internal standard (IS). The method utilized proteins precipitation with acetonitril as the only sample prep...

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Detalhes bibliográficos
Main Authors: Elgawish, Mohamed S., Mostafa, Samia M., Elshanawane, Abdalla A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744979/
https://ncbi.nlm.nih.gov/pubmed/23960741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2010.10.003
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