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Small-molecule-induced Rho-inhibition: NSAIDs after spinal cord injury

Limited axonal plasticity within the central nervous system (CNS) is a major restriction for functional recovery after CNS injury. The small GTPase RhoA is a key molecule of the converging downstream cascade that leads to the inhibition of axonal re-growth. The Rho-pathway integrates growth inhibito...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kopp, M. A., Liebscher, T., Niedeggen, A., Laufer, S., Brommer, B., Jungehulsing, G. J., Strittmatter, S. M., Dirnagl, U., Schwab, J. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744771/
https://ncbi.nlm.nih.gov/pubmed/22350947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-012-1334-7
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