SCISSOR—Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol

INTRODUCTION: The approved analgesic and anti-inflammatory drugs ibuprofen and indometacin block the small GTPase RhoA, a key enzyme that impedes axonal sprouting after axonal damage. Inhibition of the Rho pathway in a central nervous system-effective manner requires higher dosages compared with ort...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:BMJ Open
मुख्य लेखकों: Kopp, Marcel A, Liebscher, Thomas, Watzlawick, Ralf, Martus, Peter, Laufer, Stefan, Blex, Christian, Schindler, Ralf, Jungehulsing, Gerhard J, Knüppel, Sven, Kreutzträger, Martin, Ekkernkamp, Axel, Dirnagl, Ulrich, Strittmatter, Stephen M, Niedeggen, Andreas, Schwab, Jan M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BMJ Publishing Group 2016
विषय:
Neurology
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964175/
https://ncbi.nlm.nih.gov/pubmed/27466236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-010651
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