Assessment of Hepatic Detoxification Activity: Proposal of an Improved Variant of the (13)C-Methacetin Breath Test

Breath tests based on the administration of a (13)C-labeled drug and subsequent monitoring of (13)CO(2) in the breath (quantified as DOB – delta over baseline) liberated from the drug during hepatic CPY-dependent detoxification are important tools in liver function diagnostics. The capability of suc...

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Main Authors: Holzhütter, Hermann-Georg, Lock, Johan Friso, Taheri, Pouria, Bulik, Sascha, Goede, Andrean, Stockmann, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744534/
https://ncbi.nlm.nih.gov/pubmed/23967104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070780
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