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PKC Activation in Niemann Pick C1 Cells Restores Subcellular Cholesterol Transport
Activation of protein kinase C (PKC) has previously been shown to ameliorate the cholesterol transport defect in Niemann Pick Type C1 (NPC1) cells, presumably by increasing the soluble levels of one of its substrates, vimentin. This activity would then restore the vimentin cycle in these cells and a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3744505/ https://ncbi.nlm.nih.gov/pubmed/23977398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074169 |
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